How to Shut Off The “Master Switch” of Inflammation

If aches and pains are making it more and more difficult to get out of bed each day then you need to see this!


Waking up sore and achy can really zap your energy before the day even starts…

And even though many ‘experts’ would love for you to believe that it’s all part of getting older and there’s nothing you can do about it, nothing could be further from the truth!

You just need to know how to do one important thing…

What is it?

Reduce chronic inflammation.

And here’s why:

Chronic inflammation is known as the ‘silent killer’ and has been linked to a wide variety of devastating health problems including heart disease, diabetes, arthritis, and much more.

And while it may seem impossible that one thing can be responsible for so many health problems, the fact is chronic inflammation is a complex response your body has to chronic stress, poor diet, lack of exercise, and environmental toxins that sends your immune system into overdrive and it wreaks havoc on your health. 

You see, when you’re stressed your body produces a hormone called cortisol. Cortisol in small amounts can help us survive. But when it’s released by your body as a result of chronic stress, it can cause your body to store excess fat, and lead to inflammation that also causes joint pain and discomfort.


Chronic Inflammation, the root cause of disease.


So what is the best way to reduce inflammation?

That’s a great question, and the good news is that it’s actually really simple!



Of course, those are the basics, but there’s a lot more you can do!

Because inflammation is the source of pain and joint discomfort, the more you can do to reduce inflammation the more effectively heal and maintain good health.




There are powerful plant compounds such as herbs and spices that can help reduce inflammation too. In fact, ancient civilizations have used plants to treat many of the same maladies mainstream science has now linked to inflammation.

One popular example is turmeric, the yellow spice used in Ayurvedic cooking and medicine, which is widely recognized as a potent anti-inflammatory agent. But the reality is that turmeric only scratches the surface of plant compounds that help with inflammation.

The fact is, there are even more powerful anti-inflammatory compounds found in plants that are supported by a large body of clinical research to help with healthy joint function, joint health, mobility, and much more.

In fact, one herbal compound is clinically shown to support:

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What is it?

It’s known as “Indian echinacea” and “The King of Bitters,” but its proper name is Andrographis paniculata, and it’s been used for centuries in Ayurvedic medicine to alleviate joint discomfort, GI issues, malaria, fever, hepatitis, stomach ulcers, ear and skin infections, and much more. It essentially shuts off the “master switch” of inflammation.


Here’s how it works

Andrographis paniculata contains powerful anti-inflammatory compounds called andrographolides that have been shown in clinical research to exert powerful effects on the cellular pathway that triggers inflammation.

Andrographis paniculata works by activating a biochemical called PPAR-γ. It can modulate the immune response and inhibit NFkB. NFkB is like a sensor that detects dangerous pathogens and threats in your body and triggers the alert for the inflammation response to kick in.

By inhibiting NFkB, you’re reducing the activity of the overreactive tendency of the sensor so your body does not keep fighting your own cells, which is crucial to managing inflammation

‘How can I take Advantage of Andrographolides?’

Right now you can enjoy the incredible power of andrographolides’ effects on cellular inflammation and it’s easier than you thought it could be with an incredible new joint health formula that harnesses the power of andrographolide to reduce cellular inflammation at the cellular level. 


It’s called ParActin®, a patented, clinical strength Andrographis extract that is
standardized to 50% Andrographgolides. ParActin® is 50X regular strength and what
elevates this revolutionary formula above any other inflammatory management
supplement is the fact that this is the only clinically studied Andrographis extract and it
has multiple clinical trials showing reduction of swollen joints that cause people to feel
sore, stiff, and less mobile.

ParActin® has been shown in mechanism-of-action (MOA) studies to work by activating PPAR-gamma which shuts down the “master switch of inflammation” called nuclear factor kappaB (NF-kB).

NFkB is a protein that acts as a switch to turn inflammation on and off in the body. Scientists liken it to a smoke sensor that detects dangerous threats in the body such as free radicals and infectious agents like viruses and bacteria;and by deactivating NF-kB, pro-inflammatory proteins and enzymes are reduced.

And it gets even better!

In 2018, a new MOA of andrographolide of ParActin® was revealed – this research was published in Biomedical Pharmacology, a prestigious medical journal.

This new mechanism proposed that andrographolide not only reduces inflammation, but
it may also accelerate antioxidant response in the body such as glutathione, super oxide
dismutase (SOD) etc, helping to mop up cell-damaging free radicals that cause
oxidative stress.

Oxidative stress occurs when there is an imbalance between the production of free radicals and your body’s ability to counteract their damaging effects by neutralizing them with antioxidants. That’s why this new mechanism of action attributed to andrographolide is so exciting.

And the best part?

Unlike anti-inflammatories such as ibuprofen that require upwards of 1,500mg to be effective, and are often accompanied by a host of nasty side effects, the optimal of dosage of ParActin® is just 300-600mg per day!

Not only is ParActin® well tolerated but it’s also incredibly effective! Many users report feeling better within just one hour of consumption.

We know that nobody has time for aches and pains, and today science not only provides us the ability to live longer lives, but healthier and more active lives too, which is exactly what ParActin® was designed to do.

If you’re looking for a powerful ally in your quest to stay active and healthy for years to come, ParActin® may be exactly what you’re looking for.


1. Efficacy of an Andrographis paniculata composition for the relief of rheumatoid arthritis symptoms: a
prospective randomized placebo-controlled trial. Clinical Rheumatology volume 28, pages
931–946(2009) R. A. Burgos
2. Andrographolide a New Potential Drug for the Long Term Treatment of Rheumatoid Arthritis Disease.
Innovative Rheumatology Jan 2013. María A. Hidalgo et al
3. Andrographis paniculata decreases fatigue in patients with relapsing-remitting multiple sclerosis: a 12-
month double-blind placebo-controlled pilot study. BMC Neurology volume 16, Article number: 77
(2016). J. C. Bertoglio el al
4. A double‐blind, randomized, placebo‐controlled study to assess the efficacy of Andrographis paniculata
standardized extract (ParActin®) on pain reduction in subjects with knee osteoarthritis. Phytotherapy
Research. Volume33, Issue5 May 2019 Pages 1469-1479. Juan L. Hancke el al


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